目的 探讨恶性肿瘤合并疼痛患者的止痛药学监护。方法 通过对1例肺癌合并三叉神经痛患者的药学监护,探讨如何为癌痛患者制定合理的止痛治疗方案。结果 临床药师积极参与药物治疗,依据指南评价止痛治疗方案,详细采集既往用药史,强调用药依从性,给予用药教育及合理用药建议,患者疼痛得到有效控制。结论 疼痛可严重影响生活质量。临床药师可协助医生选择适宜的止痛药物、给药方式、正确联合用药、关注潜在药物相互作用,制定个体化药物治疗方案,保障癌症疼痛患者有效并合理应用止痛药物。
Abstract
OBJECTIVE To found appropriate approaches for a clinical pharmacist to carry out pharmaceutical care on patients with cancer pain. METHODS The pharmaceutical care of a patient with lung cancer and trigeminal neuralgia was analyzed to explore how to make rational analgesia therapeutic schedule for patient with cancer pain. RESULTS Clinical pharmacist actively participated in pharmacotherapy including evaluating analgesia therapeutic schedule according to guidelines, inquiring medication history, emphasizing compliance, providing medication education and rational medication recommendation. CONCLUSION Pain can make patient anxious, depressed and somnipathy. Clinical pharmacist could help physicians to select rational drug, rational administration route and rational drug combination, pay attention to drug interaction, thus to make individual therapeutic schedule and ensure the rational use of analgesic drugs.
关键词
癌痛 /
三叉神经痛 /
厄洛替尼 /
卡马西平 /
普瑞巴林 /
临床药师
{{custom_keyword}} /
Key words
cancer pain /
trigeminal neuralgia /
erlotinib /
carbamazepine /
pregabalin /
clinical pharmacist
{{custom_keyword}} /
中图分类号：
R969.3
{{custom_clc.code}}
({{custom_clc.text}})
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] WANG Z Y,ZHU B,YU B,et al. Drug therapy for cancer pain guided by clinical thinking. J Chin Pharm(中国药房),2012,23(10):943-945.[2] NCCN clinical practice guidelines in Oncology:Adult Cancer Pain. 2013.[3] Expert group of neuropathic pain treatment. Expert consensus of neuropathic pain treatment. Chin J Intern Med(中华内科杂志),2009,48(6):526-528.[4] Center for Clinical Practice at NICE(UK). Neuropathic Pain:The Pharmacological Management of Neuropathic Pain in Adults in Non-Specialist Settings. London:National Institute for Health and Clinical Excellence (UK):2010.[5] ROBERT H. DWORKIN, ALEC B. O′CONNOR, et al. Recommendations for the pharmacological management of neuropathic pain:An overview and literature update. Mayo Clin Proc, 2010, 85(3):3-14. [6] ATTAL N, CRUCCU G, BARON R, et al. EFNS Guidelines on the pharmacological treatment of neuropathic pain:2010 revision. Eur J Neurol, 2010, 17(9):1113-1188.[7] OBERMANN M, YOON M S, SENSEN K, et al.Efficacy of pregabalin in the treatment of trigeminal neuralgia. Cephalalgia, 2008, 28(2):174-181.[8] PREZ C, NAVARRO A, SALDAA M T, et al. Patient-reported outcomes in subjects with painful trigeminal neuralgia receiving pregabalin:Evidence from medical practice in primary care settings. Cephalalgia, 2009,29(7):781-790.[9] NI J X,SUN H Y. Pain Management (疼痛治疗技术) . Beijing:Beijing Medical University Press, 2010:517-526. KEEFE F J,ABEMETHY A P,CAMPBELL L C. Psychological approaches to understanding and treating disease-related pain. Annu Rev Psychol, 2005, 56:601-630. The Chinese Medical Association, Pharmacy Administration Commission, Hospital Pharmacy Commission. Guiding principles for clinical application of narcotic drugs (麻醉药品临床应用指导原则). 2007:2.
{{custom_fnGroup.title_cn}}
脚注
{{custom_fn.content}}
PDF(591 KB)
